Tirzepatide shares a similar sequence with semaglutide, but its lys side chain is modified with PEG, serving as the polypeptide’s functional group and increasing its water solubility. Tirzepatide’s primary physiological function is as a dual agonist of the glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, and it is being developed for the treatment of type 2 diabetes, having already entered clinical trials.
Technical Specifications
| Item | Specification |
|---|---|
| Product Name | Tirzepatide |
| CAS NO. | 2023788-19-2 |
| Appearance | White to off-white lyophilized powder |
| Molecular Formula | C₂₂₅H₃₄₈N₄₈O₆₈ |
| Molecular Weight | 4,813.45 g/mol |
| Amino Acid Sequence | 39-amino acid peptide with C18 diacid moiety |
| Purity (RP-HPLC) | ≥ 98.5% (UV detection at 214 nm) |
| Solubility |
Soluble in water, phosphate-buffered saline
|
| Endotoxin |
< 1.0 EU/mg
|
| Biological Activity | Dual GIP and GLP-1 receptor agonist with potent glucose-dependent insulin secretion properties |
| Storage Conditions | Store at -20°C or below in dry, light-protected conditions |
| Packaging | Available in vials of 10mg, 50mg, 100mg, and bulk custom quantities. |
| Stock Location | Stock in USA |
| MOQ | 10mg for standard sizes. Custom synthesis projects welcome. |
1.MECHANISM OF ACTION
Tirzepatide activates both the GIP and GLP-1 receptors, which are natural incretin hormone receptors involved in blood sugar regulation. The dual agonism enhances insulin secretion in a glucose-dependent manner, suppresses glucagon secretion, slows gastric emptying, and directly reduces appetite and food intake in the brain. The GIP component is believed to potentiate the effects of GLP-1, leading to greater efficacy in reducing body weight and improving insulin sensitivity.
2.PRODUCT INDICATIONS
Tirzepatide is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is also approved for chronic weight management in adults with obesity (BMI ≥30 kg/m²) or overweight (BMI ≥27 kg/m²) who have at least one weight-related comorbidity, such as hypertension, dyslipidemia, or cardiovascular disease.
3.CLINICAL EFFICACY OF PRODUCT
In the landmark SURPASS clinical trial program for diabetes, Tirzepatide demonstrated significantly greater reductions in HbA1c (up to -2.58%) compared to semaglutide and other comparators. In the SURMOUNT trials for obesity, it achieved mean weight reductions of up to 22.5% (approximately 52 lbs or 24 kg) at the highest dose over 72 weeks, establishing a new benchmark for non-surgical weight loss agents.
4.Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
We prioritize:
1.A rigorous quality management system
2.Batch traceability and stability data
3.Professional laboratory testing and validation
4.Compliance with international trade standards
Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.
5.DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation.
We can also customize packaging according to customer needs.
Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Hot Tags: Tirzepatide,Diabetes,Polypeptide,cosmetic peptide，suppliers, manufacturers, factory, customized, wholesale, buy, price, bulk, high quality, free sample，Mounjaro, Zepbound, GIP/GLP-1 receptor agonist, Dual agonist, Weight loss drug, Diabetes medication, Once-weekly injection, Eli Lilly, SURPASS trial, SURMOUNT trial,
Post time: Nov-11-2026