China PT-141 manufacturers and suppliers

PT-141

Short Description:

Bremelanotide (PT-141) Bremelanotide (PT-141) is a synthetic heptapeptide analog of α-MSH, representing a groundbreaking class of melanocortin receptor agonists that uniquely target the central nervous system to modulate sexual function.

FDA Approved Treatment

As the first FDA-approved on-demand treatment for premenopausal women with Hypoactive Sexual Desire Disorder (HSDD), it is characterized by its ability to enhance libido and arousal through brain pathways rather than peripheral vascular effects, offering a solution for individuals seeking to restore spontaneous sexual motivation without the need for daily hormonal intervention.

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Product Detail

FAQ

Product Tags

Item	Specification
Product Name	Bremelanotide (PT-141)
CAS NO.	189691-06-3/1607799-13-2
Appearance	White to off-white lyophilized powder
Molecular Formula	C50H68N14O10
Molecular Weight	1025.21 g/mol
Purity (RP-HPLC)	≥98.0%
Solubility	Soluble in water, dilute acetic acid; slightly soluble in DMSO
Endotoxin	≤1 EU/mg
Biological Activity	Potent agonist at melanocortin-4 receptor (MC4R); stimulates sexual desire and arousal
Storage Conditions	Store at -20°C, protected from light and moisture
Stock Location	Stock in USA
MOQ	1g

1 MECHANISM OF ACTION

Bremelanotide functions as a potent agonist primarily at melanocortin-4 receptors (MC4R) and to a lesser extent at MC3R located within the hypothalamus and limbic system. Upon subcutaneous administration, it crosses the blood-brain barrier to activate these receptors, triggering downstream signaling cascades that stimulate dopamine release and modulate neural circuits responsible for sexual motivation, thereby directly increasing sexual desire independently of the nitric oxide pathway utilized by traditional erectile dysfunction medications.

2 PRODUCT INDICATIONS

This product is specifically indicated for the treatment of acquired, generalized Hypoactive Sexual Desire Disorder (HSDD) in premenopausal women, addressing the distress associated with a persistent lack of sexual thoughts and receptivity. While its primary approved use is for female HSDD, it is also widely researched for its potential off-label application in treating male erectile dysfunction, particularly in cases where PDE5 inhibitors have failed, due to its central mechanism that can initiate arousal in the absence of external stimuli.

3 CLINICAL EFFICACY OF PRODUCT

Clinical trials, including the pivotal RECONNECT studies, demonstrated that bremelanotide significantly increased the number of satisfying sexual events and reduced distress related to low sexual desire compared to placebo in women with HSDD. A meaningful clinical response was achieved by approximately 25% of treated patients, with effects typically onset within 45 minutes of administration and lasting for several hours, establishing its efficacy as an as-needed therapy for restoring sexual function and improving quality of life.

4 Certificate

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

1. A rigorous quality management system
2. Batch traceability and stability data
3. Professional laboratory testing and validation
4. Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

5 DELIVERY & SHIPPING

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.

Professional and Secure Packaging
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation. We can also customize packaging according to customer needs.

Shipping Methods
Main Method: International Air Freight
We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.

Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.

We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.

Hot Tags: Bremelanotide, PT-141, Vyleesi, Melanocortin, MC4R Agonist, HSDD, Female Sexual Dysfunction, Libido, Sexual Arousal, Research Peptide, Subcutaneous Injection, Sexual Health, Peptide Therapy, Central Nervous System, Dopamine, Hypoactive Sexual Desire Disorder, Supplier, Manufacturer, Bulk order, Pharmaceutical.

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Besides, you can contact us if you have any other questions

Q1: Can i get some samples?

A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments?

A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Unionor Paypal or Escrow(Alibaba).

Q3: How to confirm the Product Quality before placing orders?

A:You can get free samples for some products,you only need to pay the shipping costor arrange a courier to us and take the samples. You can send us your product specifi-cations and requests,we will manufacture the products according to your requests.

Q4:What’s your MOQ?

A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the conditionthat sample charge is 100% paid.

Q5: How about delivery lead time?

A: Delivery lead time: About 1-3 days after payment confirmed. (Chinese holiday notincluded)

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