Sarafloxacin CAS NO. 98105-99-8
Sarafloxacin CAS NO. 98105-99-8
Technical Specifications
| Item | Specification |
|---|---|
| Product Name | Sarafloxacin |
| CAS NO. | 98105-99-8 |
| Appearance | White to pale yellow crystalline powder |
| Molecular Formula | C₂₀H₁₇F₂N₃O₃ |
| Molecular Weight | 385.36 g/mol |
| Amino Acid Sequence | Not applicable |
| Purity (HPLC) | ≥98.0% |
| Solubility | Soluble in DMSO, methanol; slightly soluble in water; insoluble in non-polar solvents |
| Endotoxin | < 1 EU/mg |
| Biological Activity | Broad-spectrum fluoroquinolone antibacterial; inhibits bacterial DNA gyrase (Topoisomerase II) and Topoisomerase IV |
| Storage Conditions | Store at 2-8°C (short term) or -20°C (long term), protected from light and moisture |
| Stock Location | USA / Germany / China (optional, based on actual stock) |
| MOQ | 1 g / 5 g / 25 g |
1. Mechanism of Action
Sarafloxacin exerts its bactericidal effect by selectively binding to and inhibiting two essential bacterial type II topoisomerases—DNA gyrase (Topoisomerase II) and Topoisomerase IV)—which prevents negative supercoiling of DNA and blocks DNA replication, transcription, and cell division, ultimately leading to double-strand DNA breaks and bacterial cell death.
2. Product Indications
This compound is indicated for veterinary pharmacological research, residue monitoring in food safety labs, and in vitro antimicrobial susceptibility studies targeting Escherichia coli, Salmonella spp., Pasteurella spp., and Staphylococcus aureus isolates from livestock and aquaculture. It is also used as an analytical reference in HPLC/MS methods for detecting fluoroquinolone residues in edible animal tissues.
3. Clinical Efficacy of Product
Although not approved for human clinical use, sarafloxacin has demonstrated high efficacy in veterinary field trials for controlling respiratory and enteric infections in cattle, swine, and poultry, with low MIC₉₀ values against common food-animal pathogens. Its excellent tissue penetration and favorable pharmacokinetic profile in animals support its historical use, while current research focuses on resistance surveillance and withdrawal period determination for food safety compliance.
4. Certificate
GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.
Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.
5. DELIVERY & SHIPPING
We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.
Each bottle of peptide is protected with a special packaging solution to ensure stability and integrity during transportation. We can also customize packaging according to customer needs.
Main Method: International Air Freight. We primarily use DHL, FedEx, UPS, and TNT because of their global reliability, speed, and advanced tracking systems. Air freight ensures the fastest transit time and minimizes the impact of environmental factors on the product.
Global Technology Co., Ltd. is a modern and advanced enterprise specializing in the production and export of active pharmaceutical ingredients (APIs), peptides, and plant extracts. The company invests in and collaborates closely with domestic manufacturers holding GMP, DMF, and FDA certifications, as well as laboratories at renowned universities, to meet diverse customer needs ranging from gram-level to ton-level. This enables Dejurui Pharmaceutical to provide customers with more flexible and convenient access to cost-effective, high-quality products and superior services.
We focus on the research and development and supply of high-quality chemical products, strictly adhering to international standards and quality systems. Our products are stable in performance and reliable in purity, widely used in industrial manufacturing, scientific research, and the fine chemical industry. We provide solid support at every stage with a professional and responsible attitude.
Besides, you can contact us if you have any other questions
Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Unionor Paypal or Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping costor arrange a courier to us and take the samples. You can send us your product specifi-cations and requests,we will manufacture the products according to your requests.
Q4:What’s your MOQ?
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the conditionthat sample charge is 100% paid.
Q5: How about delivery lead time?
A: Delivery lead time: About 1-3 days after payment confirmed. (Chinese holiday notincluded)
