TB500

Technical Specifications

Item	Specification
Product Name	TB500 (Thymosin Beta-4 Peptide)
CAS NO.	/
Appearance	White to off-white lyophilized powder
Molecular Formula	C₆₉H₁₂₃N₂₆O₂₆S
Molecular Weight	1620.96 g/mol
Purity (RP-HPLC)	≥ 98.0%
Solubility	Soluble in water or bacteriostatic water (≥2 mg/mL); stable at physiological pH
Endotoxin	≤ 1.0 EU/mg (Suitable for cell culture and in vitro studies)
Biological Activity	Lyophilized powder: Store at -20°C, protected from light and moisture (stable 24–36 months). Reconstituted solutions: Store at 2–8°C for up to 14 days or -20°C for up to 3 months
Storage Conditions	Store at 2–8°C, protected from light and moisture; stable for 24–36 months when sealed properly
Stock Location	Stock in USA
MOQ	1g

AICAR functions as an analog of adenosine monophosphate (AMP) and is phosphorylated intracellularly to ZMP (ZMP carboxamide), which mimics AMP and allosterically activates AMP-activated protein kinase (AMPK). This activation triggers downstream signaling pathways that promote catabolic processes such as fatty acid oxidation and glucose uptake while inhibiting anabolic pathways like lipid and protein synthesis. By mimicking the cellular energy deficit state, AICAR effectively reprograms metabolism to enhance energy efficiency and cellular survival, making it a powerful tool for studying metabolic adaptation, insulin resistance, and exercise mimetics in both in vitro and in vivo models.

TB500 exerts its effects by bing to acnditin, a key cytoskeletal protein, to promote cell migration and proliferation—critical processes for tissue repair and regeneration. It stimulates angiogenesis (formation of new blood vessels) to enhance nutrient and oxygen delivery to damaged tissues, while also modulating inflammatory pathways to reduce swelling and support a favorable healing environment. Additionally, TB500 upregulates the expression of growth factors and extracellular matrix components, facilitating the reconstruction of skin, muscle, tendon, and ligament structures, making it a powerful tool for studying tissue repair mechanisms in preclinical research.

TB500 is indicated for preclinical research applications focused on tissue regeneration, wound healing, and musculoskeletal repair. It is particularly relevant for studies in regenerative medicine (e.g., skin grafts, post-surgical recovery), sports science (e.g., muscle/tendon injury recovery), and biomedical research (e.g., angiogenesis, inflammation modulation). Researchers use TB500 to investigate its role in accelerating healing of chronic wounds, enhancing muscle recovery after injury, and supporting the repair of tendons, ligaments, and cartilage, providing insights into novel therapeutic strategies for tissue damage and degenerative conditions.

GlobalTech Co., Ltd. is committed to providing high-purity biotechnological peptide products, adhering strictly to quality standards and obtaining internationally recognized certifications.

Our production partners all employ GMP-compliant production systems and possess standardized quality control processes covering raw material procurement, synthesis, purification, testing, packaging, and storage. Each batch of product comes with complete documentation, including a Certificate of Analysis (COA), HPLC purity report, mass spectrometry (MS) chromatograms, and third-party testing reports available upon request.

We prioritize:

• ✔ 1. A rigorous quality management system
• ✔ 2. Batch traceability and stability data
• ✔ 3. Professional laboratory testing and validation
• ✔ 4. Compliance with international trade standards

Our commitment to quality, transparency, and regulatory compliance ensures the provision of reliable, stable, and research-grade peptide products to our global partners.

We specialize in global logistics for various cosmetic peptides. Your order will be handled with the utmost care, ensuring safe, reliable, and intact delivery.